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Oligosaccharides solution-phase alternatives

These results demonstrate that O-glycosyl trichloroacetimidate-based oligosaccharide synthesis on solid support may eventually become a valuable alternative to solution-phase synthesis because useful experience is available for the selection of the polymer support and choice of the linker system and the glycosyl donor. Further standardization of the building blocks and the protective group pattern will finally provide the yields and the anomeric control in order to successfully plan automated syntheses of oligosaccharides also in a combinatorial manner. [Pg.97]

C.K. Yemeni, V. Pathak, A.K. Pathak, ImidazoUum cation supported solution-phase assembly of homoUnear A(1 6)-linked octamannoside an efficient alternate approach for oligosaccharide synthesis, J. Org. Chem. 74 (2009) 6307-6310. [Pg.514]


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Alternate Solutions

Alternating phases

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