Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Self-displacement oligonucleotides

When purifying oligonucleotides it is particularly useful to use sample self displacement chromatography since the required component of the mixture is generally the later eluting moiety. With this approach the column loading is increased to such a point that the more strongly retained component displaces the... [Pg.51]

Additional results from AX purification of DMT-off synthetic oligonucleotides are discussed in the following section, based on the principles of displacement and sample self-displacement chromatography. [Pg.526]

Figure 9 shows an example of sample self-displacement chromatographic purification of DMT-off crude phosphorothioate oligonucleotide ISIS 2302... [Pg.527]

See other pages where Self-displacement oligonucleotides is mentioned: [Pg.390]    [Pg.526]    [Pg.527]    [Pg.527]    [Pg.528]    [Pg.528]    [Pg.655]    [Pg.485]    [Pg.196]    [Pg.134]    [Pg.115]   
See also in sourсe #XX -- [ Pg.527 ]



SEARCH



Self-displacement

© 2024 chempedia.info