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Oligonucleotide therapeutics structure

Metabolomics, Metabonomics and Metabolite Profiling 10 Ribozymes and RNA Catalysis 11 Protein-Nucleic Acid Interactions Structural Biology 12 Therapeutic Oligonucleotides... [Pg.442]

Fig. 8.4. First-generation generalized structures of natural DNA (phosphodiester) and three antisense oligonucleotide derivatives tested as antisense drugs. (Adapted from Agrawal S, Iyer RP. Perspectives in antisense therapeutics. Pharmacol Ther 1997 76 151-160 with permission.)... Fig. 8.4. First-generation generalized structures of natural DNA (phosphodiester) and three antisense oligonucleotide derivatives tested as antisense drugs. (Adapted from Agrawal S, Iyer RP. Perspectives in antisense therapeutics. Pharmacol Ther 1997 76 151-160 with permission.)...
Fig. 8.5. Structure of fomivirsen, the first marketed antisense therapeutic agent. (Adapted from Field AK. Viral targets for antisense oligonucleotides a mini review. Antiviral Res 1998 37 67-81 with permission.)... Fig. 8.5. Structure of fomivirsen, the first marketed antisense therapeutic agent. (Adapted from Field AK. Viral targets for antisense oligonucleotides a mini review. Antiviral Res 1998 37 67-81 with permission.)...
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See also in sourсe #XX -- [ Pg.2 , Pg.121 ]

See also in sourсe #XX -- [ Pg.121 ]



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