Of isoliquiritigenin

Luczkiewicz, M. and Kokotkiewicz, A. 2005. Genista tinctoria hairy root cultures for selective production of isoliquiritigenin. Zeitschrift fur Naturforschung C -... 

Maxwell, C.A. et al., Molecular characterization and expression of isoliquiritigenin 2 -0-methyltransferase, an enzyme specifically involved in the biosynthesis of an inducer of Rhizobium meliloti nodulation genes. Plant J., 4, 971, 1993. 

The chalcone dimers of the Ochnaceae differ structurally to those of the other plant families represented in Table 16.4. Compounds 147-149 and 151 are dimers in which combinations of isoliquiritigenin and davidigenin (2, 4, 4-trihydroxydihydrochalcone) are coupled through a dihydrofurano ring formed between the B-ring of one molecule (at C-3 and 4-OH) with the a- and -carbons of the other (Figure 16.9). " Similarly, the structures of... 

Isoliquiritigenin 4-glucoside Precursor of Isoliquiritigenin in [Isoliquiritigenin inhibits... 

Alternatively, chalcone reductase (CHR also known as deoxychalcone synthase) together with chalcone synthase and NADPH as a cofactor act in the formation of isoliquiritigenin, which is then isomerized, again by the enzyme chalcone isomerase, to form liquiritigenin, the precursor to daidzein, and the pterocarpan phytoalexins. A type II chalcone isomerase that seems to be found exclusively in the legumes catalyzes this isomerization reaction. Glycitein synthesis is not yet clearly defined, but is likely derived from liquiritigenin via flavonoid 6-hydroxylase, and an unidentified methyltransferase. 

Tawata, M., K. Aida, T. Noguchi, Y. Ozaki, S. Kume, H. Sasaki, M. Chin, and T. Onaya Anti-Platelet Action of Isoliquiritigenin, an Aldose Reductase Inhibitor in Licorice. Eu. J. Pharmac., 212, 87 (1992). 

Tawata M, Aida K, Noguchi T, OzaM Y, Kume S, Sasaki H, Chin M, Onaya T (1992) Antiplatelet action of isoliquiritigenin, an aldose reductase inhibitor in licorice. Eur J Pharmacol... 

Han SY, Chin Y-W, Choi YH (2013) A new approach for pharmacokinetic studies of natural products measurement of isoliquiritigenin levels in mice plasma, urine and feces using modified automated dosing/blood sampling system. Biomed Chromatogr 27 741-749... 

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