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Of 2-isocephems

Electrophilic Azidation of Chiral Lactone Enolates to Give 2-Isocephem... [Pg.643]

The lactone 2 is transformed via several steps into the 7-azido-2-isooxaphem 3 and the 7-azido-2-isocephem 4. Reduction of the azide groups, acylation and removal of the protecting groups gives the corresponding cephalosporin derivatives stereospecifically. [Pg.643]

Benzo-O-2-isocephems are obtained in high yield by fluoride-induced cyclization of readily available monocyclic /3-lactams (Scheme 138), and details of two essentially similar syntheses of 2,3-benzo-fused 1-oxacephems have appeared (Scheme 139). ... [Pg.333]

TABLE XXIII Antimicrobial Activity of 7a-Methoxy Analog of 2-lso and 0-2-Isocephems ... [Pg.359]


See other pages where Of 2-isocephems is mentioned: [Pg.63]    [Pg.63]    [Pg.430]    [Pg.430]    [Pg.529]    [Pg.358]    [Pg.358]    [Pg.326]    [Pg.111]    [Pg.144]   
See also in sourсe #XX -- [ Pg.12 , Pg.126 , Pg.127 ]

See also in sourсe #XX -- [ Pg.12 , Pg.126 , Pg.127 ]




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2-Isocephems

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