5-Octyl-2 -furanone

This modification was used in the synthesis of (-)-avenaciolide. The key step is the trans-diastereoselective Michael addition of the lithium enolate of tert-butyl 2-(phenylse-leno)propionate (THF, — 78 CC) to (R)-5-octyl-2(5//)-furanone and subsequent trans-diastereoselective iodonation318. u e... [Pg.994]

Optically active aliphatic propargylic alcohols are converted to corticoids (90% ee) via biomimetic polyene cyclization, and to 5-octyl-2(5ii)-furanone. The ee s of propargylic alcohols obtained by this method are comparable with those of the enantioselective reduction of alkynyl ketones with metal hydrides, catalytic enantioselective alkylation of alkynyl aldehydes with dialkyIzincs using a chiral catalyst ((S)-Diphenyl(l-methylpyrrolidin-2-yl)methanol) (DPMPM), and the enantioselective alkynylation of aldehydes with alkynylzinc reagents using A(A-dialkylnorephedrines. °... [Pg.361]

C12H20O3 4-hydroxy-5 octyl-2(5H)furanone 78128-84-4 518.65 45.679 1,2 24719 C12H2202 2-octynal diethyl acetal 16387-55-6 508.57 44.708 2... [Pg.515]

H)-Furanone. dihydro-5-octyl- y-dodecalactone 172a, 174b, 1053, 3266, 3370 ... [Pg.451]

Synonyms Dodecanolide-1,4 2(3H)-Furanone, dihydro-5-octyl- 4-Hydroxydodecanoic acid y-lactone y-Octyl-y-butyrolactone y-n-Octyl-y-n-butyrolactone... [Pg.1567]

Big Chemical Encyclopedia