Occupational argyria

Bleehen SS, Gould DJ, Harrington Cl, et al. 1981. Occupational argyria light and electron microscopic studies and x-ray microanalysis. Br J Dermatol 104 19-26. 

Harker JM, Hunter D. 1935. Occupational argyria. Br J Dermatol Syph 47 441-455. 

Bleehen SS, Gould DJ, Harrington CP, et al. (1981) Occupational argyria. Br J Dermatol 104 19-26 Botella R, Sastre A, Castells A (1985) Contact dermatitis to paraquat. Contact Dermatitis 13 123-124 Boyle JC, Smith NJ, Burke FD (1988) Vibration white finger. J Hand Surg Br 13 171-175... 

The majority of literature reviewed concerning the health effects of silver in humans described case reports of individuals who developed argyria following oral exposure to silver. Occupational studies describing two separate worker populations were also located. The predominant route of exposure in the occupational studies is believed to have been inhalation, but the possibility of some degree of oral or dermal exposure cannot be ruled out. Information on human exposure is limited in that the possibility of concurrent exposure to other toxic substances cannot be excluded, and the duration and level of exposure to silver generally cannot be quantitated from the information presented in these reports. 

Rosenman KD, Moss A, Kon S. 1979. Argyria Clinical implications of exposure to silver nitrate and silver oxide. J Occup Med 21 430-435. 

Silver salts in solution are skin irritants. Silver nitrate can cause discoloration (argyria). Occupational contact allergy to silver is rarely reported (Marks 1966). Silver nitrate for patch testing is commercially available (Chemotechnique Diagnostics 1998). 

Hydroquinone may induce depigmentatioriy however seldom, from exposure in photography. Single cases of argyria have been reported from occupational expo-... 

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