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Obese gene weight control

Neuropeptide Y. Neuropeptide Y is identical with melanostatin. It is one of the most abundant neuropeptides. It stimulates food intake. Leptin blocks Neuropeptide Y gene expression and its release fix>m the hypothalamus. But whether this effect is responsible for a role of leptin in weight control and prevention of obesity is not clear. [Pg.316]

The importance of leptin to obesity is dramatically illustrated in mice. Mice lacking leptin are obese and will lose weight if given leptin. Mice that lack the leptin receptor are insensitive to leptin administration. Preliminary evidence indicates that leptin and its receptor play a role in human obesity, but the results are not as clear-cut as in the mouse. The interplay of genes and their products to control caloric homeostasis will be an exciting area of research for some time to come. [Pg.1267]

Sakane N, Yoshida T, Umekawa T, Kogure A, Takakura Y, Kondo M. Effects of Trp64Arg mutation in the beta 3-adrenergic receptor gene on weight loss, body fat distribution, glycemic control, and insulin resistance in obese type 2 diabetic patients. Diabetes Care. 1997 20 1887-1890. [Pg.113]

See other pages where Obese gene weight control is mentioned: [Pg.405]    [Pg.405]    [Pg.2661]    [Pg.29]    [Pg.106]    [Pg.107]    [Pg.423]    [Pg.755]    [Pg.240]    [Pg.131]    [Pg.350]    [Pg.480]    [Pg.423]    [Pg.755]    [Pg.146]    [Pg.1407]    [Pg.1885]    [Pg.411]    [Pg.411]    [Pg.885]    [Pg.249]    [Pg.17]    [Pg.715]    [Pg.102]    [Pg.104]    [Pg.108]    [Pg.24]    [Pg.153]    [Pg.157]    [Pg.619]    [Pg.203]    [Pg.8]    [Pg.300]   
See also in sourсe #XX -- [ Pg.380 , Pg.381 , Pg.402 ]



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