OATP organic anion polymorphism

Nozawa, T., Nakajima, M., Tamai, I., Noda, K., Nezu, J., Sai, Y., Tsuji, A., Yokoi, T., Genetic polymorphisms of human organic anion transporters OATP-C (SLC21A6) and OATP-B (SLC21A9) allele frequencies in the Japanese population and functional analysis, J. Pharmacol. Exp. Ther. 2002, 302, 804-813. 

M. Iwai, H. Suzuki, I. Ieiri, K. Otsubo, and Y. Sugiyama. Functional analysis of single nucleotide polymorphisms of hepatic organic anion transporter OATP1B1 (OATP-C). Pharmacogenetics 14 749-757 (2004). 

Nozawa, T., Minami, H., Sugiura, S., Tsuji, A., and Tamai, 1. (2005) Role of organic anion transporter OATPIBI (OATP-C) in hepatic uptake of irinotecan and its active metabolite, 7-ethyl-10-hydroxycamptothecin in vitro evidence and effect of single nucleotide polymorphisms. Drug Metab. Dispos. 33, 434—439. 

Niemi, M., Schaeffeler, E., Lang, T., et al. (2004) High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCOIBI). Pharmacogenetics. 14, 429-440. 

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