Nutritional encephalomacia vitamin

The nervous system is also affected in deficiency, with the development of central nervous system necrosis (nutritional encephalomacia), a condition that can be exacerbated by feeding a diet especially rich in polyunsaturated fatty acids. There is also axonal dystrophy in animals maintained for prolonged periods of time on vitamin E-deficient diets. Synthetic antioxidants, but not selenium, can prevent these changes. The neuropathy begins from axonal membrane injury, and then develops as a distal and dying-back type of axonopathy. 

Vitamin E deficiency in chicks may lead to a munber of distinct diseases myopathy, encephalomalacia and exudative diathesis. In nutritional myopathy the main muscles affected are the pectorals, although the leg muscles also may be involved. Nutritional encephalomalacia, or crazy chick disease , is a condition in which the chick is imable to walk or stand and is accompanied by haemorrhages and necrosis of brain cells. Exudative diathesis is a vascular disease of chicks characterised by a generahsed oedema of the subcutaneous fatty tissues, associated with an abnormal permeabUity of the capUlary walls. Both selenium and vitamin E appear to be involved in nutritional myopathy and in exudative diathesis, but the element does not seem to be important in nutritional encephalomacia. It should be stressed that sele-niiun itself is a very toxic element and care is required in its use as a dietary additive. The toxic natine of seleniiun is discussed in Chapter 7. 

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See also in sourсe #XX -- [ , , ]

See also in sourсe #XX -- [ , ]

See also in sourсe #XX -- [ , ]

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