Nucleoside diphosphates, glycosyl

Thus, O-glycosyl trichloroacetimidates exhibit in terms of ease of formation, stability, reactivity, and general applicability outstanding glycosyl donor properties they resemble in various aspects the natural nucleoside diphosphate sugar derivatives. Thus, this method has become a very competitive alternative to the existing techniques. 

Biosynthetic studies on the formation of hyaluronic acid have yielded less information than have similar studies about the structure of chondroitin. Addition to small, well defined oligosaccharides has not been found. Using labelled nucleoside 5 -glycosyl diphosphates in a bacterial system, evidence has been obtained for the synthesis of hyaluronic acid of high molecular... 

Glycosyl—Enzyme Complex Intermediates in Biosynthesis of Complex Saccharides. The synthesis of nucleoside diphosphate sugars involves the transfer of a nucleotidyl group from a nucleoside triphosphate to a sugar 1-phosphate with the simultaneous release of pyrophosphate according to the following general reaction (11) ... 

Thus, X may be a saccharide, a 1,2-glycal, a phosphate residue, a nucleoside diphosphate, or a polyprenol diphosphate and X the OH of water, an alcohol, and often a saccharide. It is convenient, however, to consider enzymes cleaving polysaccharide chains in one of four classes hydrolases, glycosyl transferases, lyases, and phosphorylases. These follow the general reactions discussed below. 

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