Nucleophilic substitution reactions monolayers

A detailed study of nucleophilic substitution reactions in silyl chloride monolayers on the Si/SiC>2 surface showed results similar to those observed on the Au surface. Well-packed monolayers with Br terminal groups undergo substitution readily with small nucleophiles (such as N3- ion) but, with bulky nucleophiles, reaction does not go to completion. Sterically undemanding reaction with tin radicals proceeded rapidly and quantitatively. The possibility of condensation between two adjacent chains in the monolayer facilitated by their close proximity was also discussed325. 

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