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Nucleophilic substitution and reduction reactions of amides

Amides (RCONH2, RCONHR or RCONHR2) are much less reactive than acid [Pg.175]

Reduction of primary amides (RCONH2) forms primary amines (RCH2NH2), while secondary (RCONHR) and tertiary (RCONR2) amides can be reduced into secondary (RCH2NHR) and tertiary (RCH2NR2) amines, respectively. It should be noted that these reactions do not involve nucleophilic substitution of the NH2 (or NHR or NR2) group of the amide. [Pg.175]

See other pages where Nucleophilic substitution and reduction reactions of amides is mentioned: [Pg.150]    [Pg.175]    [Pg.175]   


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Amidating reaction

Amidation reactions

Amidation reductive

Amide Reaction

Amide nucleophilic substitution reactions

Amides nucleophiles

Amides nucleophilic

Amides reduction

And nucleophilic substitution

And substitution reactions

Nucleophiles and reactions

Nucleophiles substitution reactions

Nucleophilic substitution and reduction

Nucleophilic substitution reactions nucleophiles

Of nucleophilic substitution reactions

Reaction substituted and

Reactions of Amides

Reduction of amides

Reduction reactions amides

Substituted amides

Substitution reactions nucleophile

Substitution reactions nucleophilic

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