Nuclear male sterility

Hofig KP, Moller R, Donaldso L, Putterill J, Walter C (2006) Towards male sterility in Pinus radiata - a stilbene synthase approach to genetically engineer nuclear male sterility. Plant Biotechnol J 4 333-343... 

The production of single crosses or three-way hybrids using cytoplasmic male sterility and nuclear fertility restorer system is widely used. Genic male sterility was used for the production of hybrid seeds in the early 1970s in France and Romania. The first hybrids produced in this way were introduced in the United States in 1972 (4). 

Lindquist, A. W., Use of Sexually Sterile Males for Eradication of Screw-Worms, Proc. Second Inter-American Symposium on Peaceful Application of Nuclear Energy, pp. 229-35, Buenos Aires, June 1-5, 1959. 

Certain aspects of the pathology of vitamin E deficiency suggest that nucleic acid metabolism may be deranged. In tissues severely affected by the deficiency one sees various nuclear changes. These include an increase in numbers of nuclei in rabbit skeletal muscle, appearance of giant multi-nucleated cells in rat testes (Mason, 1933), and the appearance of many multinucleated erythroid precursors in vitamin E-deficient monkey bone marrow (Porter et al., 1962). It is of course well known that these tissues are dramatically affected by vitamin E deficiency in the various species. In the rabbit one sees nutritional muscular dystrophy, in the male rat sterility, and in the monkey macrocytic anemia (Dinning and Day, 1957a). 

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