Notholaenic acid

Notholaenic acid (109) from Notholaena standleyi afforded anti-HSV-I activity at a relatively high concentration (25 fxg/disk) (Rinehart et al., 1990). 

Lunularic acid (100), a natural dihydrostilbene growth inhibitor found in liverworts 74) and also in algae (75), has not yet been detected in ferns. A related compound notholaenic acid (101) occurs as a frond exudate component of two gymnogrammoid ferns 76) and is reported to have photosynthesis inhibiting activity on chloroplast (77) and also antimicrobial activity 78). Ternatin (102), in which a benzene ring is linked to a monoterpene unit to form a chromene ring, has been isolated from Sceptridium ternatum 79) and S.japonicum 80). 

Notholaenic acid Notholaena chilensis Sturm. C17H18O5 81... 

---