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Nosiheptide, synthesis

Related Pd-cyclizations have been applied to the synthesis of 3-carboethoxy-2-trifluoromethylindoles [367, 368] and 2-carbobenzyloxy-4-hydroxymethyl-3-methylindoles, a unit that is present in the antibiotic nosiheptide, from a 2-(2-iodoanilino) unsaturated ester [369]. A nice variation utilizes the in situ synthesis of 2-iodoanilino enamines and subsequent cyclization [370] as shown below. [Pg.140]

Koerber-Ple, K. Massiot, G. Synthesis of an unusual 2,3,4-trisubstituted indole derivative found in the antibiotic nosiheptide. Synlett 1994, 759-760. [Pg.55]

Micrococcin Pj. C4gH4,N,30,S , Mr 1144.36, mp. 252°C (decomp.), [a] +1 i6° (90% C2H5OH). A peptide antibiotic isolated from the culture broth of Bacillus pumilus as main component of the micrococcin P complex. For synthesis see Zir.. Closely related with M. is the antibiotic nosiheptide. ... [Pg.398]

See other pages where Nosiheptide, synthesis is mentioned: [Pg.153]    [Pg.104]    [Pg.403]    [Pg.462]    [Pg.153]    [Pg.120]    [Pg.121]    [Pg.288]    [Pg.334]    [Pg.181]    [Pg.395]    [Pg.401]    [Pg.401]   
See also in sourсe #XX -- [ Pg.403 ]



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Nosiheptide

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