Northrup. John

NORTHRUP, JOHN H. (1891-1987). An American chemist who won a Nobel prize in chemistry in 1946 along with James B. Sumner and Wendell M. Stanley. His work was primarily concerned with isolation and crystallization of enzymes. Many first included the production of the enzyme trypsin in the laboratory and isolation of the first bacterial virus. He was also responsible for producing diphtheria antitoxin in crystalline form. His education was at eastern schools including Harvard. Yale, and Princeton. 

Like many classic contributions to science, this spectacular advance was initially met with criticism and even derision. However, Sumner was not deterred he took his show on the road and, through demonstration, convinced many scientists of the protein nature of enzymes. Subsequently, a number of enzymes were crystallized in the 1930s by John Northrup and Moses Kunitz and were also shown to be proteins. These later preparations were essentially pure. Northrup and Kunitz demonstrated that enzyme activity paralleled the amount of protein present, laying the issue to rest. Sumner and Northrup shared the 1946 Nobel Prize in Chemistry. ... 

Nauck MA, Duran S, Kim D, Johns D, Northrup J, Festa A, et al. A comparison of twice-daily exenatide and biphasic insulin aspart in patients with type 2... 

The revised publication. Corrosion Tests and Standards Application and Interpretation, is sponsored by ASTM Committee G1 on Corrosion of Metals and edited by Robert Baboian, RB Corrosion Service. Section editors include Robert Baboian, Sheldon W. Dean, Dean Corrosion Technology, Harvey P. Hack, Northrup Grumman Corporation, Edward Hibner, Special Metals Corporation, and John R. Scully, University of Virginia. This is the second edition of Manual 20 in the ASTM Manual series. 

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