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Nootkatone Botryosphaeria dothidea

Biotransformation of Nootkatone (2) by Fusarium culmorum AND Botryosphaeria dothidea... [Pg.913]

The expensive grapefruit aromatic, nootkatone (2) used by cosmetic and fiber manufacturers was obtained in high yield by biotransformation of (+)-valencene (1), which can be cheaply obtained from Valencia orange, by Chlorella species, fungi such as Mucor species, Botryosphaeria dothidea, and Botryodiplodia theobromae. This is a very inexpensive and clean oxidation reaction, which does not use any heavy metals, and thus this method is expected to find applications in the industrial production of nootkatone. [Pg.741]

The biotransformation of 2 by Aspergillus niger and Botryosphaeria dothidea resembled to that of the oral administration to rabbit since the ratio of the major metabolites 115- (6) and 1 l/ -nootkatone-11,12-diol (7) was similar. It is noteworthy that the biotransformation of 2 by Fusarium culmorum affords stereospecifically nootkatone-11/ , 12-diol (7) (Noma et al., 2001a) (Figure 15.10). [Pg.746]


See other pages where Nootkatone Botryosphaeria dothidea is mentioned: [Pg.550]    [Pg.908]    [Pg.738]    [Pg.741]    [Pg.746]   
See also in sourсe #XX -- [ Pg.913 , Pg.914 , Pg.915 ]




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Botryosphaeria dothidea

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