Nontoxic lipid significance

Results of chemical analysis showed that the glucosamine and total fatty acid contents of the KDO depleted, toxic lipid A and the nontoxic lipid A were essentially the same but that the nontoxic lipid A was significantly lower in the phosphorus content (Table V). The molar ratio of glucosamine phosphorus fatty acids was 2 2 4 for the toxic lipid A and 2 1 4 for the nontoxic lipid A. The relative molar distribution of normal fatty acids (lauric, myristic, and palmitic acids) and the 3-hydroxymyristic acid did not indicate a correlation between the content of these components and toxicity. The nontoxic lipid A possessed as high a tumor regression activity when combined with CWS as did the purified... 

Mercury is essentially nontoxic in its elemental form (Hg ). In the absence of any chemical or biological system that chemically alters Hg , it can be consumed orally without any significant side effects. However, once Hg is chemically modified to the ionized, inorganic species, Hg T it becomes toxic. Further bioconversion to an alkyl Hg, such as methyl Hg (CHaHg ), yields a very toxic species of Hg that is highly selective for lipid-rich tissue, such as the neuron. The relative order of toxicity is as follows ... 

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