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Nonsteroidal anti-inflammatory drugs bleeding risk with

Concomitant use of heparin and oral anticoagulants can increase the risk for bleeding due to the antiplatelet effect of aspirin. In addition, use with alcohol can increase the risk of Gl bleeding. / spirin displaces a number of drugs (e.g., tolbutamide, nonsteroidal anti-inflammatory drugs [NSAIDs], methotrexate, phenytoin, and probenecid) from protein binding sites in the blood. Corticosteroid use can reduce serum salicylate levels by increasing the clearance of aspirin. [Pg.32]

Nonsteroidal anti-inflammatory drugs (NSAIDs) Standard dosage regimens of aspirin or traditional NSAIDs (e.g., ibuprofen) selective cyclooxygenase-2 (COX-2) inhibitors should be used in patients at risk for upper Gl bleeding use with caution in renal insufficiency... [Pg.732]

See other pages where Nonsteroidal anti-inflammatory drugs bleeding risk with is mentioned: [Pg.862]    [Pg.1163]    [Pg.113]    [Pg.136]    [Pg.90]    [Pg.772]    [Pg.41]    [Pg.605]    [Pg.3112]    [Pg.614]    [Pg.1843]    [Pg.112]    [Pg.76]    [Pg.49]    [Pg.249]    [Pg.252]    [Pg.13]    [Pg.193]    [Pg.74]   
See also in sourсe #XX -- [ Pg.1697 ]



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