Noninvasive monitoring, tissue-specific

In vivo 19F MR spectroscopy has been shown to be a highly specific, noninvasive tool for identifying and monitoring fluorinated compounds and metabolites. This technology is complementary to other structural and functional imaging tools, and often a combination of approaches is required to address specific questions. Although almost all 19F MR examinations are limited by the relatively low SNR of the spectra, fluorine MR spectroscopy has a unique role in clinical research applications and can provide a direct measurement of drug uptake in tissue. 

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