Nongenomic Actions of Retinoids

In addition to its genomic functions, retinoic acid tdso has a number of nongenomic functions. It enhances the stability of keratin mRNA, leading to increased synthesis of this protein (Crowe, 1993). Retinoic acid acts edso tis tm effector in response to tremsmembrane signaling by retinoylation of target 

In the synthesis of most glycoproteins containing mannose, the intermediate carrier of the mcmnosyl moiety is the polyene dolichol phosphate. However, in some systems, retinyl phosphate can act as the intermediate carrier between UDP-mcumose tmd the acceptor glycoprotein. Retinyl phosphate mannose seems to be involved especially in the synthesis of hydrophobic regions of glycoproteins (DeLuca, 1977 Frot-Coutaz et al., 1985). 

---