Noncovalent Glycan Arrays

FIGURE 15.1 Noncovalent immobilization methods to construct a glycan array. 

---

An elegant alternative approach for noncovalent interaction relies on fluorous-lluorous interactions. A glycan array of monosaccharides and disaccharides bearing anomeric fluorous tags was noncovalently immobilized on fluorous-derivatized glass slides (19, 20). The attachment method is compatible with a wide range of functional groups and has been successfully used to probe carbohydrate-protein interactions. 

---