Nonchromatographic Separation Process Description

This chapter provides (i) a brief review of the chemistry involved in chiral host-chiral guest recognition involving primary amines (ii) a description of a nonchromatographic (equilibrium or bind-release based) separation process devel-... 

Invariably the analytical method developer is required to make compromises between the amount and complexity of the sample processing and the separating power, selectivity, and other attributes of the chromatographic or nonchromatographic determination. These compromises are often strongly influenced by the projected cost and time required for various method options and by the desired quality, detail, and reliability of the results. Major issues usually are the availability of laboratory or field equipment and instrumentation, the experience and skill of the staff in using the equipment, and other laboratory or field infrastructure required to complete the analyses of the samples. Most research and standard analytical methods contain many compromises that may not be clearly defined in the method description, but should be understood by the user. 

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