Nonadrenergic, noncholinergic nervous system

Table 6-1 Some of the Transmitter Substances Found in Autonomic Nervous System (ANS), Enteric Nervous System (ENS), and Nonadrenergic, Noncholinergic Neurons.1...

The list of neurons that possess nNOS continues to expand (Vincent and Hope, 1992 Bredt et al., 1991). For example, NO has emerged as a major nonadrenergic noncholinergic transmitter in the enteric nerves (Bult etal., 1990 Desai etal., 1991). In addition to the nervous system, immunore-activity and/or mRNA transcript for nNOS have been detected in skeletal muscle (Nakaneeta/., 1993 Weiner eta/., 1994), pancreatic )8-ceils (Schmidt et al., 1992), the male sex organ (Burnett et al., 1992), the pituitary gland (Wolff and Datto, 1992), the adrenal medulla (Afework et al., 1994 Dun et al., 1993), and the macula densa and distal nephron of the kidneys (Mundel et al., 1992 Terada et al., 1992 Wilcox et al., 1992). Therefore, nNOS is expressed in diverse cell types and tissues. 

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