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NMR of Nucleic Acids

Chi-Wan Chen and Jack S. Cohen introduce the application of - P NMR to DNA and RNA conformations. High-resolution P NMR of transfer ribonucleic acids and P studies on drug-nucleic acid complexes (prepared by the editor with Evelyn M. Goldfield) are then presented. Phillip A. Hart introduces phosphorus relaxation methods, which are shown to provide important information on the conformation and dynamics of nucleic acids and phosphoproteins. Thomas L. James delves further into relaxation behavior of solution-state nucleic acids, and Heisaburo Shindo completes this section by describing solid-state " P NMR of nucleic acids. [Pg.2]


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