Nitrosative stress oxygen/nitrogen

In general, oxidative and nitrosative stress result from an imbalance between an overproduction of reactive oxygen species (ROS) and reactive nitrogen species (RNS) on one side and a deficiency of enzymatic and... 

Inflammatory reactions, oxidative stress (increase in production of reactive oxygen species, ROS), and nitrosative stress (increased generation of reactive nitrogen species, RNS) are major components of secondary injury. All these processes play a major role in regulating the pathogenesis of acute and chronic TBI (Fig. 6.1). 

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