Nitropyrazines reduction

Reduction of 2,6-diamino-3,5-dinitropyrazine in dimethylacetamide with hydrogen over platinum oxide (or with sodium sulfide and ammonium chloride in water at room temperature) gave 2,3,5-triamino-6-nitropyrazine (1180), but reduction with hydrogen and 10% palladium on charcoal at 50p.sJ. gave tetraamino-pyrazine (1180). 2-Amino-5hydrochloric acid at reflux gave 2-chloro-5-(3, 3 -dimethylureido)-... 

By reduction of nitropyrazines (nuclear, extranuclear primary) Section 7.1.2. 

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