2-nitrophenyl isonitrile

SYNS BENZENE, 1-ISOCYANO-4-NITRO- p-NITROPHENYL ISOCYANIDE 4-NITROPHENYL ISOCYANIDE p-NITROPHENYL ISONITRILE PHENYL ISOCYANIDE, p-NITRO-... 

NITRO-l,4-PHENYLENEDIAMINE see ALL750 4-NITRO-l,2-PHENYLENEDIAMINE see ALL500 o-NITRO-p-PHENYLENEDIAMINE (MAK) see ALL750 4-NITROPHENYL ISOCYANIDE see IKH780 p-NITROPHENYL ISOCYANIDE see IKH780 p-NITROPHENYL ISONITRILE see IKH780... 

Finally, siliranes have been allowed to react for the first time with isocyanides. Phenyl isonitrile 47 and /7-nitrophenyl isonitrile 48 underwent insertion into the Si-C bond at room temperature with formation of the silacyclobutanimines 49-51 [17]. 

Gilley CB, Kobayashi Y (2008) 2-nitrophenyl isocyanide as a versatile convertible isocyanide rapid access to a fused y-lactam (3-lactone bicycle. J Org Chem 73 4198 204 Chen JJ, Golebiowski A, Klopfenstein SR, West L (2002) The universal Rink-isonitrile resin applications in Ugi reactions. Tetrahedron Lett 43 4083 085 Hulme C, Peng J, Morton G, Salvino JM, Herpin T, Labaudiniere R (1998) Novel safety-catch linker and its application with a Ugi/De-BOC/Cyclization (UDC) strategy to access carboxylic acids, 1, 4-benzodiazepines, diketopiperazines, ketopiperazines and dihydroqui-noxalinones. Tetrahedron Lett 39 7227-7230... 

This procedure illustrates the best way to prepare aryl isocyanides. It is quite general, having been used by Ugi and Meyr e to make the following isocyanides from the corresponding form-amides phenyl (56%), />-tolyl (66%), 2,6-dimethylphenyl (88%), mesityl (80%), o-chlorophenyl (43%), -chlorophenyl (54%), 2-chloro-6-methylphenyl (87%), -methoxyphenyl (64%), p-di-ethylaminophenyl (75%), -nitrophenyl (41%), and 2-naphthyl (50%). Aliphatic isonitriles are generally best prepared by a simpler procedure involving the action of phosphorus oxychloride on an N-alkylformamide in the presence of pyridine.7... 

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