Nitroacetone reactions with

H)-Naphthalenone, 4,4a,5,6,7,8-HEXAHYDRO-, 46, 80 Nitroacetone, 46, 3 />-Nitrobenzaldehyde, 46, 36 Nitrosation of N-phenylglycine, 46, 96 N-Nitroso-N-phenylglycine, 46, 96 reaction with acetic anhydride to yield 3-phenylsydnone, 46, 96 Nitrosyl chloride, addition to bicyclo [2.2.1]hepta-2,S-diene, 46, TS Nonane, 1,1,3-trichloro-, 46,104 Noriricvclanol, 46, 74 oxidation by chromic acid, 46, 78 NortricyclanOne, 46, 77 Nortricyclyl acetate, 46, 74 from bicyclo[2.2.1]hepta-2,5-dlene and acetic acid, 46, 74 saponification of, 46, 75... 

Isatin has been reported to yield 3-nitrocinchoninic acid (92 R = C02H) with nitromethane in aqueous KOH.83 Although this seems like the use of a type 1 synthon, it is more appropriate to regard it as another example of a methazonic acid reaction. The reaction of nitroacetone with o-aminobenz-aldehyde leads to 2-methyl-3-nitroquinoline derivatives.84... 

Pvrrolor3.2- 1pvridines The synthesis of the aromatic pyrrolo[3,2- ]pyridine ring system was achieved by a variation of the Leimgruber-Bathcho indole synthesis (9.101 The 5-nitro-6-methylpyridine required by this scheme was prepared by treatment of a solution of nitroacetone and 9 in ethanol at -IQPC with sodium acetate, followed by the addition of ammonium acetate and heating at reflux. This reaction proved to be reproducible, reliably affording 26 in modest yield (44%). 

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