Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Nitro group aliphatic, useful reactions

Table 3 (No. 16) shows that ( )-p-nitro-cmnamate or derivatives can be reduced by enoate reductase, too. However, this reaction can be performed only with isolated enoate reductase using NADH as electron donor. Reduced methylviologen spontaneously reacts with nitro groups. Aliphatic as well as aromatic nitro compounds are also reduced by ferredoxins present in clostridia (26). Table 3 (No. 16) shows that ( )-p-nitro-cmnamate or derivatives can be reduced by enoate reductase, too. However, this reaction can be performed only with isolated enoate reductase using NADH as electron donor. Reduced methylviologen spontaneously reacts with nitro groups. Aliphatic as well as aromatic nitro compounds are also reduced by ferredoxins present in clostridia (26).
Nitro Compounds. Under mild conditions, aromatic nitro compounds are hydrogenated easily to amines.518 The reaction may give partially reduced products, according to the circumstances. Palladium, platinum, and nickel are used frequently for this reaction. For example, nitro and benzyl ester functions are reduced on Pd(OH)2/C on THF and on Pd/C in EtOH.519 Aliphatic nitro groups are reduced more slowly. [Pg.193]

A nitro group may also be introduced by the oxidation of oximes. For this, salts of hypobromous acid are generally used. This method is sometimes applied for the preparation of aliphatic nitro compounds. The reaction proceeds in the following way (Forster [206], Cherkasova and Mehrikov [207], Iffland et al. [208]) ... [Pg.131]

The synthetic importance of reaction (a) ° comes from the fact that it reduces to one step the pathway for conversion of an acid chloride into a nitrile (instead of the classical and rather inconvenient two-step route via an acid amide). Reaction is an example of a new transformation for aliphatic amines. Previously, there were no methods available for the direct transformation of an amino into a nitro group and the stepwise procedures were too cumbersome to be of practical use. Transformation of a nitro group into a carbonyl is a well-known reaction. Its modification, shown in reaction represents a welcome opportunity to obtain a protected carbonyl group as the immediate result of such a transformation. The viability of the sequential reactions (b) plus (c) enables the employment of a > CHNH2 moiety as a synthetic equivalent to a protected carbonyl group. A one-pot sequence of imine formation and its reduction with sodium triacetoxyborohydride represents a convenient... [Pg.116]

Aliphatic nitro compounds are hydrogenated under the same conditions used for the reduction of aromatic nitro groups. They follow the same reaction path as illustrated in Scheme 19.1 for aromatic nitro compounds, but they are hydrogenated somewhat less readily than the aromatic species (Eqn. 19.21). 5 Double bonds are hydrogenated in preference to the aliphatic nitro group but not carbonyl or oximino groups. 6> ... [Pg.484]

The hydrogenation of aliphatic nitro groups takes place with retention of configuration when the reaction is run under the normal conditions. The basic nature of Raney nickel does not promote epimerization of the nitro group before hydrogenation at low temperatures but the alkaline impurity found in platinum oxide does. The use of platinum oxide in ethanol resulted in the formation of a mixture of product stereoisomers but, in acetic acid, retention of configuration was observed. Higher temperatures also promoted inversion (Eqn. 19.24).5>... [Pg.485]


See other pages where Nitro group aliphatic, useful reactions is mentioned: [Pg.224]    [Pg.115]    [Pg.870]    [Pg.1553]    [Pg.56]    [Pg.585]    [Pg.182]    [Pg.493]    [Pg.1171]    [Pg.17]    [Pg.27]    [Pg.129]    [Pg.158]    [Pg.75]    [Pg.1216]    [Pg.241]    [Pg.870]    [Pg.779]    [Pg.501]    [Pg.315]    [Pg.245]    [Pg.15]    [Pg.870]    [Pg.255]    [Pg.821]    [Pg.226]    [Pg.226]    [Pg.430]    [Pg.255]    [Pg.245]    [Pg.891]    [Pg.157]    [Pg.533]    [Pg.476]    [Pg.348]    [Pg.392]    [Pg.441]    [Pg.557]    [Pg.563]    [Pg.571]    [Pg.980]    [Pg.333]    [Pg.821]    [Pg.780]   
See also in sourсe #XX -- [ Pg.366 ]




SEARCH



Groups, use

Nitro group

© 2024 chempedia.info