Nitric oxide myoglobin

During the curing process, some of the nitrites are converted to nitric oxide. This combines with the myoglobin proteins in the muscle of the meat to form the deep red nitric oxide myoglobin, which causes cured meats such as ham to turn pink during the smoking process. 

Fox, J. B., and Ackerman, S. A. (1968). Formation of nitric oxide myoglobin Mechanisms of the reaction with various reductants. J. Food Set. 33, 364-370. 

Koizumi, C., and Brown, W. D. (1971). Formation of nitric oxide myoglobin by nicotinamide adenine dinucleotides and flavins. J. Food Sci. 36, 1105-1109. 

Reith, J. F., and Szakaly, M. (1967a). Formation and stability of nitric oxide myoglobin. 

The dissociation of carboxymyoglobin and nitric oxide myoglobin are described by similar expressions with smaller values for L. 

Dee, G., Rice-Evans, C., Obeyesekera, S., Meraji, S., Jacobs, M. and Bruckdorfer, K.R. (1991). The modulation of ferryl myoglobin formation and its oxidative effects on low density liproprotein by nitric oxide. FEBS Lett. 294, 38-42. 

This same group developed a novel biosensor based on manganese myoglobin to detect nitric oxide. Mn-containing myoglobin was chosen as... 

S. Kroning, F.W. Scheller, U. Wollenberger, and F. Lisdat, Myoglobin-clay electrode for nitric oxide (NO) detection in solution. Electroanalysis 16, 253—259 (2004). 

G.C. Zhao, X.W. Wei, and Z.S. Yang, A nitric oxide biosensor based on myoglobin adsorbed on multi-walled carbon nanotubes. Electroanalysis 17, 630-634 (2005). 

Nitrosylmyoglobin (NO-Mb) Nitric oxide complex with myoglobin Intact Fe(II) Native Red... 

Zhao et al. [104] reported the electrochemical behavior of myoglobin on MWCNT-GCE and the potential application for the development of a nitric oxide biosensor. Myoglobin was immobilized on the acid-treated-MWCNTs-GCE by dipping the electrode into 0.24 mM myoglobin solution (in acetate buffer pH 5.6) over 72 hours. After that, the electrode was removed, washed with water and stored at 4 °C. Electrochemical impedance spectroscopy experiments... 

---