Nitration of 1,10-phenanthrolines

Reports of further studies of the nitration of 1,10-phenanthroline have appeared. Nitration with fuming nitric acid and concentrated sulfuric acid at 160°-170° gives 5-nitro-1,10-phenanthroline (75%) and 4,5-diazafluorenone (13%).252... 

The first nitration of 1,10-phenanthroline in one of the pyridine rings has been accomplished by the use of fuming nitric acid in acetic anhydride.252 In this way 3-nitro-1,10-phenanthroline was obtained in very low yield. The mechanism proposed for the nitration is the same as that previously proposed for the similar nitration of quinoline.277 4,5-Diazafluorenone was again a coproduct. 

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See also in sourсe #XX -- [ ]

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