Nickel trifluoromethyl derivative

At the present time the preparation of the trifluoromethylated derivatives of low valent transition metals by ligand-exchange reactions appears to be quite general. However, as exemplified by the nickel reaction above, the utility of the method is obviously subject to the inherent stability of the desired product. In many cases, such as the preparation of the trifluoromethyl derivatives of the cyclopentadienyl cobalt system, (CF3)Co(Cp)(CO)I and (CF3)2Co(Cp)(CO), the reaction of the dihalide with (CF3)2Cd glyme represents the simplest reaction... 

L. Zhang, M. Brookhart, P. White, Synthesis, characterization, and ethylene polymerization activities of neutral nickel(II) complexes derived from anilino-substituted enone ligands bearing trifluoromethyl and trifluoroacetyl substituents. Organometallics 25(8), 1868-1974 (2006)... 

Various trifluoromethylated metalloporphyrins 54 were prepared in high yields by the reaction of brominated metalloporphyrins 53 (copper and nickel complexes) with stoichiometric amounts of FS02CF2C00Me/CuI in the presence of catalytic amounts of a palladium catalyst [28]. Similarly, the (CF3)2Cd-CF3CdBr-CuBr system was used as a source of trifluoromethyl anion in the synthesis of some porphyrin derivatives [29]. 

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