Next-generation sequencing applications

Applications of Next-Generation Sequencing Technologies to the Study of the Human Microbiome... 

In recent years, new reports suggest that novel next-generation sequencing (NGS) technology has the potential to quickly supersede microarrays in a wide range of applications (80,87). This seems reasonable because in principle NGS can overcome the limitations (1-3) cited above (88). Although it may seem a reasonable evolution, especially when NGS becomes more robust and affordable, the fact is that in 2013 microarrays are still in use and, indeed, microarrays are still the option of choice for many studies where the flexibility of NGS may not be necessary. Whether they will disappear or will stay as one more technique is something that is yet to be seen. 

Metzker ML. Applications of next-generation sequencing. Sequencing technologies - the next generation. Nat Rev Genet 2010 ll(l) 31-46. 

MacLean, D., Jones, J.D.G., Studhokne, D.J., 2009. Application of "next-generation" sequencing technologies to microbial genetics. Nature Reviews. Microbiology 7 (4), 287-296. 

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