New Nuphar Alkaloids

New Nuphar alkaloids isolated since 1974 are listed in Table I. Table 1 includes monomeric CIS alkaloids and dimeric sulfur-containing alkaloids. 

5-(3-Furyl)-8-methyloctahydroindolizine (4) was isolated from Castor fiber L. and is the first example of a Nuphar alkaloid with an indolizine chromophore (26). Structure 4 was proposed by the examination of mass spectra. 

Name Source Melting point Md (solvent) Molecular formula, M Reference(s) 

5-(3-Furyl)-8-methyl- Castor fiber L. Amorphous — c h19no, 26 

6 -Epihydroxythiobi- Nuphar lutea Presence shown by spectral 33 

---