Neurotoxic syndrome

Evans, W. C. 1976. Bracken thiaminase-mediated neurotoxic syndromes. Pages 113-131 in E. H. Perring and B. G. Gardiner (eds.), The biology of bracken. Linnean Society of London-Academic Press, London. 

DNLM 1. Substance-Related Disorders--physiopathology. 2. Brain-drug effects. 3. Neurotoxicity Syndromes—etiology. 4. Substance-Related Disorders—complications. WM 270 N4943 2007] I. Title. 

In general, the clinical presentation of the human diseases associated with the ingestion of marine seafood toxins is similar to that of any other food poisoning disease. However, a number of clinical issues make these diseases particularly difficult to diagnose and treat. For example, the neurotoxic syndromes associated with CFP, PSP, and NSP represent points along a continuum of disease severity rather than clinically exclusive diseases. Even if fish or other seafood is the suspected source of a disease outbreak, diarrhea associated with the outbreak could be misdiagnosed as originating from bacterial rather than from phycotoxin contamination. 

Compared to controls, 41 MEK workers with an average of 14 years exposure exhibited significantly lower motor nerve conduction velocities in the median, ulnar, and peroneal nerves irritation of the eyes and upper respiratory tract and a neurotoxic syndrome characterized by mood disorders, irritability, memory difficulties, sleep disturbances, headache, and numbness were also more prevalent in the exposed workers/... 

The halogenated hydroxyquinolines include iodoquinol and clioquinol. Their mechanism of action is unknown. These agents can produce severe neurotoxicity and clioquinol is believed to have been responsible for the neurotoxic syndrome subacute myelo-optic neuropathy (SMON). 

Reeves RR, Mack JE, Beddingfield JJ. Neurotoxic syndrome associated with risperidone and fluvoxamine. Ann Pharmacother 2002 36(3) 440-3. 

Neurological symptoms occur in more than 20% of patients with cancer and can be increased by cytostatic drugs. Acute and late neurotoxic syndromes involve a number of cytostatic agents (Table 4). 

Hartman, DE. 1995. Neuropsychological toxicology Identification and assessment of human neurotoxic syndromes (second edition). New York, NY Plenum Press, 132-133. 

Juntenen J. Neurotoxic syndromes and occupational exposure to solvents. Environ Res 1993 60(1) 98 111. 

Hartman DE Neuropsychological toxicology of metals, in Neuropsychological Toxicology Identification and Assessment of Human Neurotoxic Syndromes. New York, Pergamon, 1988, pp 55-107... 

DNLM 1. Environmental Illness—etiology. 2. Neurotoxicity Syndromes. 3. Mental Disorders—etiology. 4. Neurotoxins— adverse effects. WL 140 B878e 2002]... 

Hartman, D. E. 1978. Identification and assessment of human neurotoxic syndromes. In Neuropsychological Toxicology, pp. 217-221. New York Pergamon. 

A retrospective study of patient records revealed 5 patients with bipolar affective disorder, treated with lithium carbonate 900 mg to 2.4 g daily, who had developed a reversible neurotoxic syndrome with ataxia, dysarthria. 

D.E.Hartman, Neuropsychological Toxicology Identification And Assessment of Human Neurotoxic Syndromes. 2nd Ed. Plenum Press, New York, 1995. 

Carod-Artal FJ (2(X)3) Neurological syndromes linked with the intake of plants and fungi containing a toxic component. I. Neurotoxic syndromes caused by the ingestion of plants, seeds and fruits. Rev Neurolog 36 860-871... 

Pyrethroid insecticides are generally classified into one of two large groups on the basis of the central neurotoxic syndrome that they produce [5, 6]. Type I pyrethroids are esters of chrysanthemic acid and an alcohol, having a furan ring and terminal side chain moieties, and absence of a cyano moiety. Allethrin was the first pyrethroid identified in 1949. Allethrin and other pyrethroids such as phenothrin and permethrin with the basic cyclopropane carboxylic ester structure are type I pyrethroids. The insecticidal activity of these synthetic pyrethroids was enhanced further by the addition of a cyano group to give ot-cyano type II pyrethroids such as deltamethrin, fenvalerate, cyfluthrin, cyhalothrin, and lambda-cyhalothrin (Fig. 137.2). 

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