Neurons retinal

Percupo CM, Hooks JJ, Shinohara T, Caspi R (1990) Detrick B Cytokine-mediated activation of a neuronal retinal resident cell provokes antigen presentation. 1 Immunol 145 4101 107. 

CNG channels are expressed in retinal photoreceptors and olfactory neurons, and play a key role in visual and olfactory signal transduction. In addition, CNG channels are found at low density in some other cell types and tissues such as brain, testis, and kidney. While the function of CNG channels in sensory neurons has been unequivocally demonstrated, the role of these channels in other cell types, where expression has been observed, remains to be established. Based on their phylogenetic relationship, the six CNG channels... 

Zenisek D, Steyer JA, Eeldman ME, Aimers W (2002) A membrane marker leaves synaptic vesicles in nulliseconds after exocytosis in retinal bipolar cells. Neuron 35 1085-1097 Zhang L, He T, Talal A, Wang G, Frankel SS, Ho DD (1998) In vivo distribution of the human immunodeficiency virus/simian immunodeficiency virus coreceptors CXCR4, CCR3, and CCR5. J Virol 72 5035-5045... 

Neurotrophin 4/5 is not as well characterized as other members of the neurotrophin family. Much of what is known is derived from analysis of NT4/5 and TrkB knockout mice. Elucidating the actions of NT4/5 is complicated by virtue of the fact that both NT4/5 and BDNF exert their effects via the TrkB receptor. It appears that NT4/5 functions largely overlap with those of other neurotrophin family members, particularly BDNF. NT4/5 knockout mice are essentially normal, in contrast to BDNF knockout mice, which do not live long. NT4/5 is likely to have unique actions on a subpopulation of neurons in the nodose and geniculate ganglia, which are not supported by BDNF. Like BDNF, NT4/5 acts on sensory neurons and retinal ganglion cells, supporting their survival. 

Absorption of light causes inhibition of vertebrate photoreceptor cells, which then initiate programs of responses among retinal neurons 807... 

Campbell, D. S. and Holt, C. E. Chemotropic responses of retinal growth cones mediated by rapid local protein synthesis and degradation. Neuron 2001, 32, 1013-1026. 

Accelerated apoptotic cell death has been observed in many neurodegenera-tive diseases such as Alzheimer s disease (K7), Huntington disease (W9), amyotrophic lateral sclerosis (K12), cerebellar degeneration (T4), neuron degeneration in Down s syndrome (B16), Parkinson s disease (J1), and retinitis pigmentosa (R1). 

Foster This would be tricky with a normal mammalian retina because of the presence of the rods and cones, although possible on a rodless+coneless mouse retina. In David Person s studies he identified the ganglion cells projecting to the SCN using dye injections into the SCN that retrolabelled the ganglion cells of the retina. He then recorded from these identified cells. But of course there may be more than one population of intrinsically photosensitive inner retinal neuron. 

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