Neurons glutamate receptors

Tse FW, Tse A, HiUe B, Horstmann H, Aimers W (1997) Local Ca + release from internal stores controls exocytosis in pituitary gonadotrophs. Neuron 18 121-132 Tu JC, Xiao B, Yuan JP, Lanahan AA, Leoffert K, Li M, Linden DJ, Worley PF (1998) Homer binds a novel proUne-rich motif and links group 1 metabotropic glutamate receptors with 1P3 receptors. Neuron 21 717-726... 

Hollman, M and Heinemann, S (1994) Cloned glutamate receptors. Arm. Rev. Neurosci. 17 31-108. Lerma, J (1997) Kainate reveals its targets. Neuron 19 1155-1158. 

L-Glutamate acts as an excitatory neurotransmitter at many synapses in the mammalian central nervous system. Electrophysiological measurements and the use of various selective agonists and antagonists indicate that different glutamate receptors co-exist on many neurons. 

Armstrong, N. and Gouaux, E., Mechanisms for activation and antagonism of the AMPA-sensitive glutamate receptor crystal structures of the GluR2 ligand binding core, Neuron, 28, 165-181, 2000. 

The NMDA receptor is an ionotropic glutamate receptor involved in fast excitatory neurotransmission. It plays a key role in a variety of CNS functions, most notably long-term potentiation (LTP) and neuronal plasticity, and is regulated by several mechanisms. One such mechanism involves the amino acid glycine (1). 

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