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Neuromuscular junction tools

Because many toxins have highly specific actions at receptors and at ion channels they have found much use as laboratory research tools to elucidate basic biological mechanisms. Black widow spider venom and alpha-bungarotoxin from the cobra are classic examples which block the acetylcholine (ACh) receptor at the neuromuscular junction. [Pg.201]

A. Postsynaptic Neurotoxins. Postsynaptic neurotoxins are an indispensable tool in neurochemistry as they are a good antagonist to acetylcholine, a nerve transmitter. By using a neurotoxin, one can determine the number of acetylcholine receptors (AChR) in a given neuromuscular junction. Using this technique, it was found that myasthenia gravis patients have much less AChR than normal persons. [Pg.57]

See other pages where Neuromuscular junction tools is mentioned: [Pg.107]    [Pg.186]    [Pg.8]    [Pg.34]    [Pg.192]    [Pg.193]    [Pg.57]    [Pg.83]    [Pg.83]    [Pg.83]    [Pg.93]    [Pg.512]    [Pg.109]    [Pg.404]    [Pg.776]    [Pg.436]    [Pg.418]   
See also in sourсe #XX -- [ Pg.275 ]



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Neuromuscular

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