Nerve agents hydrolytic catalytic activity

Table I. Hydrolytic catalytic activity, Kd (sec ), of selected enzymes toward some nerve agents...

Enzymes found in hepatocytes,64 neuronal cells,65 and plasma also hydrolyze nerve agents, albeit comparatively weakly. Study of the requirements for hydrolysis at the enzyme active sites could potentially lead to the design of more efficient hydrolytic enzymes that could be used as catalytic scavengers.66... 

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