Neolitsea sericea

Fig. (5). Sesquiterpenes from Taiwania cryptomerioides and Neolitsea sericea...

Fig. (6). Structures of squamocin from Uvaria pauci-ovulata and lanostanes from Neolitsea sericea...

Another recent example for a similar enolate fragmentation to construct a 10-membered ring is represented by the last step of the sericenine (108 Scheme 36) synthesis. (108) is a constituent of the essential oil of the leaves of Neolitsea sericea (Lauraceae), which grows in the southern parts of Japan and China. The tosyloxy ester (107) gives directly the furanogermacradiene (108), presumably via die neo-sericenine with the c s-a,3-unsaturated ester group, which isomerizes to the thermodynamically favored product. 

The tree bark of Neolitsea sericea (Blume) Koidz. (Lauraceae) has yielded a wide variety of aporphine alkaloids, one of which is A -methyl-actinodaphnine (XCIXa), C19H19O4N (mp 206°, [a] +59° in ethanol) identical with the A"-methylation product from authentic actino-daphnine (XCIXb) (67). 

Yoon, W., Moon, J. Y, Kang, J. Y, Kim, G. 0., Lee, N. H., and Hyun, C. G. (2010a). Neolitsea sericea essential oil attenuates LPS-induced in ammation in RAW264.7 macrophages by suppressing NF-kappaB and MAPK activation. IVaf. Prod. Commun. 5(8), 1311-1316. 

A. niger also converted shiromodiol diacetate (136) isolated from Neolitsea sericea to 2p hydroxy derivative (137) (Nozaki et al., 1996) (Figure 20.45). 

Komae H, Hayashi N 1971 Palmitone and phytosterols from Neolitsea sericea. Phytochemistry 10 1953-1954... 

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