Natural pro ducts

Mikoiajczyk M, Balczewski P (2003) Phosphonate Chemistry and Reagents in the Synthesis of Biologically Active and Natural Pro ducts. 223 161 -214 Mikoiajczyk M, see Drabowicz J (2000) 208 143 -176... 

Lee, M. L, Schneider, G., Scaffold architecture and pharmacophoric properties of natural products and trade drugs application in the design of natural pro-duct-based combinatorial libraries,... 

As stated in Sect. 1, there are a number of reviews [19-29] and monographs [30-32] on the quinazolines and quinazoline alkaloids. Also the synthesis of heterocyclic natural products by the aza-Wittig method has been reviewed recently by Eguchi [108-110], and Fresneda and Molina have reviewed timely the application of iminophosphorane-based methodologies for the synthesis of natural pro ducts [ 111 ]. In this section, selected topics on synthesis of quinazoline alkaloids will be discussed retrospectively focusing on these synthetic methodologies. 

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