Nanofibrous drug delivery system

Figure 73 Representative 3-D nanostructured scaffolds for bone-specific drug delivery systems, (a) Electrospun sitk scaffold with BMP-2 loaded, scale bar=5 pm (reprinted from Ref. [86] with permission) (b) Self-assembled peptide-amphiphile (PA) nanofibers network, scale bar= 1 mi (reprinted from Ref. [87] with permission) (c) Nanocrystalline apatite modified poly(lactide-co-glycolide) (PLAGA) microsphere scaffolds, scale bar=2pm (reprinted from Ref. [88] with permission) and (d) poly(L-lactic acid) (PLLA) nanofibrous scaffolds incorporated with poly(lactic-co-glycolic acid) (PLGA) nanospheres, scale bar=2 pm (reprinted from Ref. [89] with permission).

Katti, D.S., Robinson, K.W., Ko, F.K., and Laurencin, C.T., 2004. Bioresorbable nanofibre-based systems for wound healing and drug delivery Optimization of fabrication parameters. Journal of Biomedical Materials Research, 70B(2), pp. 286—96. 

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