N-Thiocarbonylation

Deoxygenation of sec-alcohols.1 2 -Deoxynucleosides (1) can be deoxygen-ated efficiently to 2 3 -dideoxynucleosides (3) by reaction with N,N -thiocarbonyl-diimidazole in DMF (80°) to form imidazolides, which on reaction with methanol are converted into methylthionocarbonates (2). These crystalline derivatives are reduced by Bu3SnH to 3. 

Dioxoosmium(VI) porphyrins were used to prepare dinitrogenosmium(II) porphyrins (path 1, P = OEP, TTP) via reduction with hydrazine hydrate in THF. The latter were transformed into bisalkoxides (path m) by autoxidation in alcohols, in dibromides (path n), thiocarbonyls (path p), nitridoosmium(VI) alkoxides (path q), or osmochromes (path r), respectively. 

N-Thiocarbonyl alkyl esters of amino acids were chromatographed by Halpern et al. [286]. Their preparation proceeds according to Scheme 5.29. The reaction sequence includes esterification of amino acids followed by reaction with carbon disulphide and triethylamine, giving rise to dithiocarbamate. Reaction of the latter with chloroformate... 

Fur die Synthese von 1,3-Thiazolen aus Halogenmethyl-Verbindungen sind als Eddukte in breitem MaBe N-Thiocarbonyl-carbamidin-Strukturen eingesetzt worden, wobei ein Amino-Rest als Abgangsgruppe dient. Aus N-Thioacyl-carbamidinen und a-Halogen-ketonen erhalt man 5-Acyl-l,3-thiazole ... 

JCS(P1)2665>. The N-thiocarbonyl analogues 34 similarly afford thiazoles 35 <97JCS(P1)2673>. 

N-alkoxythiocarbamyl-imidazoles benzimidazoles N,N, carbonyldiimidazole N,N -thiocarbonyldiimidazole s. under N,N -Thiocarbonyl-di(azoles)... 

Phenyltetrazole and phenyl isothiocyanate 14 at elevated temperature gave the 1,3,4-thiadiazole derivative 15 in 64% yield via the N-thiocarbonyl nitrile imine intermediate 16. ... 

Ozy-2-oso-3-oyan-indolin 22, 373. X.N -Ozalyl-benzamldin 24 II 210. 6.7-MethylendiQxy-ahmazolin 27 I 824. C HgN,O.S JN -Fhenyl-N -thiocarbonyl-ozamid 12, 2SS. 

N-Thiocarbonylation s. Thiol-urethans from amines Thiocarbonyl compds. 

N,N -Thiocarbonyl-diimidazole Hemato porphyrin Tetramethylguanidine Di-o-tolylguanidine 2,4-Diguanidinophenyl lauryl ether l-Guanyl-3,6-dipyr azole nitrate... 

R CN2 (354 R = Bu, R =H, R =Me) is also obtained from BuC sCSSiMe and Me2CN2 ". N,N -thiocarbonyl diimidazole combines with CH2N2, N2CHC02Et, 2-furyldiazomethyl ketone, or 2-thienyldiazo-methylketone, in the presence of NEt, to form the 1,3,4-thiadi-... 

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