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N-Hydroxysulfosuccinimide

Staros, J.V. (1982) N-hydroxysulfosuccinimide active esters Bw(N-hydroxysulfosuccinimide) esters of two dicarboxylic acids are hydrophilic, membrane impermeant, protein cross-linkers. Biochemistry 21, 3950-3955. [Pg.1117]

Staros, J.V., Wright, R.W., and Swinghe, D.M. (1986) Enhancement by N-hydroxysulfosuccinimide of water-soluble carbodiimide-mediated coupling reactions. Anal. Biochem. 156, 220-222. [Pg.1117]

EDC-mediated coupling This step is crucial for the success of the immobilization procedure. EDC reacts with the carboxyl groups to form an amine-reactive O-acylisourea intermediate. If this intermediate does not encounter an amine, it will hydrolyze and regenerate the carboxyl group. In the presence of N-hydroxysulfosuccinimide (Sulfo-NHS), efficiency of EDC coupling is increased by the formation of an amine-reactive Sulfo-NHS ester intermediate, which has... [Pg.68]

Another example of the synthesis of cross-hnked HA with a dihydrazide bridge is described in [29]. For a formation of the bond between hyaluronan and primary amine, carbodiimide and N-hydroxysulfosuccinimide were used. The authors synthesized many... [Pg.125]

See other pages where N-Hydroxysulfosuccinimide is mentioned: [Pg.157]    [Pg.172]    [Pg.216]    [Pg.237]    [Pg.287]    [Pg.766]    [Pg.1043]    [Pg.147]    [Pg.193]    [Pg.259]    [Pg.694]    [Pg.127]    [Pg.546]    [Pg.213]    [Pg.152]    [Pg.127]    [Pg.173]    [Pg.239]    [Pg.674]    [Pg.255]    [Pg.387]    [Pg.172]    [Pg.2155]    [Pg.299]    [Pg.258]    [Pg.129]    [Pg.121]   


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N-hydroxysulfosuccinimide sulfo-NHS)

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