N-Deprotection and Intramolecular Amide Bond Formation

5 Ketopiperazines, 2,5-Diketopiperazines and Quinoxalines by Ugi-4CR with N-Deprotection and Intramolecular Amide Bond Formation 

The UDC strategy is suitable for solid-phase synthesis and many methods that use this strategy have been reported. The Hulme group [75] described a 

The synthesis of biologically significant quinoxalinones utilizing the UDC methodology was recently reported by Hulme et al. [78] who used the reaction between N-Boc-protected 1,2-phenylenediamines, glyoxylic acids, aldehydes, and iso- 

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