Myoglobin, antigenic structure

Although the last decade has witnessed a great deal of activity investigating the immunochemistry of protein antigens, so far the antigenic structure of sperm whale myoglobin and of lysozyme have been completed. ... 

Arnon R, Sela M, Yaron A, Sober HA (1965) Polylysine-specific antibodies and their reaction with oligolysines. Biochemistry 4 948-953 Atassi MZ (1975) Antigenic structure of myoglobin the complete immunochemical anatomy of a protein and conclusions relating to antigenic structures of proteins. Immunochemistry 12 423-438... 

Atassi MZ (1977) The complete antigenic structure of myoglobin. In Atassi MZ (ed) Immunochemistry of proteins, vol II. Plenum, New York Atassi MZ, Habeeb AFSA (1977) The antigenic structure of hen eggwhite lysozyme A model for disulfide-containing proteins. In Atassi MZ (ed) Immunochemistry of proteins, vol II. Plenum, New York... 

Modification of protein side chains has not been extensively employed in studies of functional sites, and, where it has been used, little has been done to characterize the nature of the products by either chemical or physical methods. This approach, used in its fullest capacity to delineate the complete antigenic structures of sperm whale myoglobin (Atassi, 1975) and lysozyme (Atassi et al., 1976a,b Lee and Atassi, 1977a,b Atassi and Lee, 1978, Atassi, 1978), could be of great value... 

Fig. 4-8 Stylized representations of protein structures in which a helices are represented as coiled ribbons and p strands are represented by arrows pointing in the N — C direction, p proteins contain predominantly /3-sheet structure (e.g., retinol binding protein and the antigen binding fragment of antibodies) while a proteins contain predominantly a helices (e.g., myoglobin), alp proteins contain a mixture of a helix and p sheet (e.g., triosephosphate isomerase).

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