Myers Synthetic Approach to Dynemicin

in order to select between these various options and formulate a viable retrosynthetic analysis, the Myers group experimented with several model systems and carefully considered published studies toward related targets, such as calicheamicin y5 (4), in order to get a qualitative feel for just how sensitive these different 

Having removed the enediyne portion of the molecule, only a few modifications remained to complete this retrosynthetic analysis. 

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