Myeloid lung tumors

Fig. 3.1 Dose-incidence curves for different neoplasms in animals exposed to external radiation (A) myeloid leukemia in x-irradiated mice (°) (Upton et al., 1958) (B) mammary gland tumors at 12 months in gamma-irradiated rats (A) (Shellabarger et al., 1969) (C) thymic lymphoma in x-irradiated mice ( ) (Kaplan and Brown, 1952) (D) kidney tumors in x-irradiated rats (o) (Maldague, 1969) (E) skin tumors in alpha-irradiated rats (percentage incidence x 10) ( ) (Bums et al., 1968) (F) skin tumors in electron-irradiated rats (percentage incidence x 10) (A) (Bums et al., 1968) (G) reticulum cell sarcoma in x-irradiated mice (0) (Metalli et al., 1974) (H) lung adenomas in neutron-irradiated mice ( ) (Ullrich et al., 1976) (Modified from UNSCEAR, 1972) (from Upton, 1984).

G-CSF receptor through which pegfilgrastim and filgrastim act has been found on tumor cell lines including some myeloid, T lymphoid, lung, head and neck and bladder tumor cell lines... 

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